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Population pharmacodynamic modeling of intramuscular and oral dexamethasone and betamethasone effects on six biomarkers with circadian complexities in Indian women

Population pharmacokinetic/pharmacodynamic (PK/PD) analysis was performed for extensive data for differing dosage forms and routes for dexamethasone (DEX) and betamethasone (BET) in 48 healthy nonpregnant Indian women in a partial and complex cross-over design. Single doses of 6 mg dexamethasone pho...

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Detalles Bibliográficos
Autores principales: Krzyzanski, Wojciech, Milad, Mark A., Jobe, Alan H., Peppard, Thomas, Bies, Robert R., Jusko, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099395/
https://www.ncbi.nlm.nih.gov/pubmed/33954911
http://dx.doi.org/10.1007/s10928-021-09755-y