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Population pharmacodynamic modeling of intramuscular and oral dexamethasone and betamethasone effects on six biomarkers with circadian complexities in Indian women
Population pharmacokinetic/pharmacodynamic (PK/PD) analysis was performed for extensive data for differing dosage forms and routes for dexamethasone (DEX) and betamethasone (BET) in 48 healthy nonpregnant Indian women in a partial and complex cross-over design. Single doses of 6 mg dexamethasone pho...
Autores principales: | Krzyzanski, Wojciech, Milad, Mark A., Jobe, Alan H., Peppard, Thomas, Bies, Robert R., Jusko, William J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099395/ https://www.ncbi.nlm.nih.gov/pubmed/33954911 http://dx.doi.org/10.1007/s10928-021-09755-y |
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