Detecting placebo and drug effects on Parkinson's disease symptoms by longitudinal item‐score models

This study tested the hypothesis that analyzing longitudinal item scores of the Unified Parkinson's Disease Rating Scale could allow a smaller trial size and describe a drug's effect on symptom progression. Two historical studies of the dopaminergic drug ropinirole were analyzed: a cross‐o...

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Detalles Bibliográficos
Autores principales: Chen, Chao, Jönsson, Siv, Yang, Shuying, Plan, Elodie L., Karlsson, Mats O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099436/
https://www.ncbi.nlm.nih.gov/pubmed/33951753
http://dx.doi.org/10.1002/psp4.12601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099436/
https://www.ncbi.nlm.nih.gov/pubmed/33951753
http://dx.doi.org/10.1002/psp4.12601

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