A novel method based on unbiased correlations tests for covariate selection in nonlinear mixed effects models: The COSSAC approach

Building a covariate model is a crucial task in population pharmacokinetics and pharmacodynamics in order to understand the determinants of the interindividual variability. Identifying a good covariate model usually requires many runs. Several procedures have been proposed in the past to automatize...

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Detalles Bibliográficos
Autores principales: Ayral, Géraldine, Si Abdallah, Jean‐François, Magnard, Claude, Chauvin, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099437/
https://www.ncbi.nlm.nih.gov/pubmed/33755345
http://dx.doi.org/10.1002/psp4.12612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099437/
https://www.ncbi.nlm.nih.gov/pubmed/33755345
http://dx.doi.org/10.1002/psp4.12612

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