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A novel method based on unbiased correlations tests for covariate selection in nonlinear mixed effects models: The COSSAC approach
Building a covariate model is a crucial task in population pharmacokinetics and pharmacodynamics in order to understand the determinants of the interindividual variability. Identifying a good covariate model usually requires many runs. Several procedures have been proposed in the past to automatize...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099437/ https://www.ncbi.nlm.nih.gov/pubmed/33755345 http://dx.doi.org/10.1002/psp4.12612 |