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MicroRNA-499 serves as a sensitizer for lung cancer cells to radiotherapy by inhibition of CK2α-mediated phosphorylation of p65

The present study aimed to define the tumor-suppressive role of microRNA-499 (miR-499) in lung cancer cells and its underlying mechanism. First, qRT-PCR analysis revealed poor expression of miR-499 in clinical samples and cell lines of lung cancer. Next, we performed loss- and gain-of-function exper...

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Detalles Bibliográficos
Autores principales: Ma, Yu-Shui, Shi, Bo-Wen, Lu, Hai-Min, Xie, Peng-Fei, Xin, Rui, Wu, Zhi-Jun, Shi, Yi, Yin, Yu-Zhen, Hou, Li-Kun, Jia, Cheng-You, Wu, Wei, Lv, Zhong-Wei, Yu, Fei, Wang, Gao-Ren, Liu, Ji-Bin, Jiang, Geng-Xi, Fu, Da
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099482/
https://www.ncbi.nlm.nih.gov/pubmed/33997273
http://dx.doi.org/10.1016/j.omto.2021.03.016