Development of Perphenazine-Loaded Solid Lipid Nanoparticles: Statistical Optimization and Cytotoxicity Studies

OBJECTIVE: Perphenazine (PPZ), as a typical antipsychotic medical substance, has the same effectiveness compared to atypical antipsychotic medications for the treatment of schizophrenia. Despite the lipophilic essence, PPZ encounters limited bioavailability caused by the first-pass metabolism follow...

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Detalles Bibliográficos
Autores principales: Farsani, Parisa Abbasi, Mahjub, Reza, Mohammadi, Mojdeh, Oliaei, Seyed Sajad, Mahboobian, Mohammad Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099510/
https://www.ncbi.nlm.nih.gov/pubmed/33997026
http://dx.doi.org/10.1155/2021/6619195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099510/
https://www.ncbi.nlm.nih.gov/pubmed/33997026
http://dx.doi.org/10.1155/2021/6619195

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