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Development of Perphenazine-Loaded Solid Lipid Nanoparticles: Statistical Optimization and Cytotoxicity Studies

OBJECTIVE: Perphenazine (PPZ), as a typical antipsychotic medical substance, has the same effectiveness compared to atypical antipsychotic medications for the treatment of schizophrenia. Despite the lipophilic essence, PPZ encounters limited bioavailability caused by the first-pass metabolism follow...

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Detalles Bibliográficos
Autores principales:	Farsani, Parisa Abbasi, Mahjub, Reza, Mohammadi, Mojdeh, Oliaei, Seyed Sajad, Mahboobian, Mohammad Mehdi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099510/ https://www.ncbi.nlm.nih.gov/pubmed/33997026 http://dx.doi.org/10.1155/2021/6619195

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