Induced lineage promiscuity undermines the efficiency of all-trans-retinoid-acid-induced differentiation of acute myeloid leukemia

All-trans retinoid acid (ATRA) can induce terminal differentiation of acute promyelocytic leukemia (APL), also known as the M3 subtype of acute myeloid leukemia (AML). However, non-APL types of AML respond poorly to ATRA-induced differentiation, and the mechanism underlying cell-type-specific resist...

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Detalles Bibliográficos
Autores principales: Tang, Yijia, Tian, Xin, Xu, Zihan, Cai, Junke, Liu, Han, Liu, Nan, Chen, Zhu, Chen, Saijuan, Liu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099557/
https://www.ncbi.nlm.nih.gov/pubmed/33997692
http://dx.doi.org/10.1016/j.isci.2021.102410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099557/
https://www.ncbi.nlm.nih.gov/pubmed/33997692
http://dx.doi.org/10.1016/j.isci.2021.102410

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