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Induced lineage promiscuity undermines the efficiency of all-trans-retinoid-acid-induced differentiation of acute myeloid leukemia

All-trans retinoid acid (ATRA) can induce terminal differentiation of acute promyelocytic leukemia (APL), also known as the M3 subtype of acute myeloid leukemia (AML). However, non-APL types of AML respond poorly to ATRA-induced differentiation, and the mechanism underlying cell-type-specific resist...

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Detalles Bibliográficos
Autores principales:	Tang, Yijia, Tian, Xin, Xu, Zihan, Cai, Junke, Liu, Han, Liu, Nan, Chen, Zhu, Chen, Saijuan, Liu, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099557/ https://www.ncbi.nlm.nih.gov/pubmed/33997692 http://dx.doi.org/10.1016/j.isci.2021.102410

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