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Oxidative damage to hyaluronan–CD44 interactions as an underlying mechanism of action of oxidative stress-inducing cancer therapy

Multiple cancer therapies nowadays rely on oxidative stress to damage cancer cells. Here we investigated the biological and molecular effect of oxidative stress on the interaction between CD44 and hyaluronan (HA), as interrupting their binding can hinder cancer progression. Our experiments demonstra...

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Detalles Bibliográficos
Autores principales: Yusupov, Maksudbek, Privat-Maldonado, Angela, Cordeiro, Rodrigo M., Verswyvel, Hanne, Shaw, Priyanka, Razzokov, Jamoliddin, Smits, Evelien, Bogaerts, Annemie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099558/
https://www.ncbi.nlm.nih.gov/pubmed/33895486
http://dx.doi.org/10.1016/j.redox.2021.101968