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Anion-exchange HPLC assay for separation and quantification of empty and full capsids in multiple adeno-associated virus serotypes

Gene therapy has entered a new era where numerous therapies for severe and rare diseases are generating robust and compelling clinical results. The rapid improvements in gene therapies over the past few years can be attributed to better scientific understanding of the critical quality attributes tha...

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Detalles Bibliográficos
Autores principales: Khatwani, Santoshkumar L., Pavlova, Anna, Pirot, Zhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099603/
https://www.ncbi.nlm.nih.gov/pubmed/33997103
http://dx.doi.org/10.1016/j.omtm.2021.04.003