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Anion-exchange HPLC assay for separation and quantification of empty and full capsids in multiple adeno-associated virus serotypes
Gene therapy has entered a new era where numerous therapies for severe and rare diseases are generating robust and compelling clinical results. The rapid improvements in gene therapies over the past few years can be attributed to better scientific understanding of the critical quality attributes tha...
Autores principales: | Khatwani, Santoshkumar L., Pavlova, Anna, Pirot, Zhu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099603/ https://www.ncbi.nlm.nih.gov/pubmed/33997103 http://dx.doi.org/10.1016/j.omtm.2021.04.003 |
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