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CD11b Deficiency Exacerbates Methicillin-Resistant Staphylococcus aureus-Induced Sepsis by Upregulating Inflammatory Responses of Macrophages

Macrophages are important for the first line of defense against microbial pathogens. Integrin CD11b, which is encoded by Itgam, is expressed on the surface of macrophages and has been implicated in adhesion, migration, and cell-mediated cytotoxicity. However, the functional impact of CD11b on the in...

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Detalles Bibliográficos
Autores principales: Sim, Hyunsub, Jeong, Daecheol, Kim, Hye-In, Pak, Seongwon, Thapa, Bikash, Kwon, Hyung-Joo, Lee, Keunwook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099615/
https://www.ncbi.nlm.nih.gov/pubmed/33996169
http://dx.doi.org/10.4110/in.2021.21.e13