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Hypertrophic preconditioning cardioprotection after myocardial ischaemia/reperfusion injury involves ALDH2-dependent metabolism modulation

Brief episodes of ischaemia and reperfusion render the heart resistant to subsequent prolonged ischaemic insult, termed ischaemic preconditioning. Here, we hypothesized that transient non-ischaemic stress by hypertrophic stimulation would induce endogenous cardioprotective signalling and enhance car...

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Detalles Bibliográficos
Autores principales: Ma, Lei-Lei, Ding, Zhi-Wen, Yin, Pei-Pei, Wu, Jian, Hu, Kai, Sun, Ai-Jun, Zou, Yun-Zeng, Ge, Jun-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099646/
https://www.ncbi.nlm.nih.gov/pubmed/33910156
http://dx.doi.org/10.1016/j.redox.2021.101960