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Delivery technologies for T cell gene editing: Applications in cancer immunotherapy

While initial approaches to adoptive T cell therapy relied on the identification and expansion of rare tumour-reactive T cells, genetic engineering has transformed cancer immunotherapy by enabling the modification of primary T cells to increase their therapeutic potential. Specifically, gene editing...

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Detalles Bibliográficos
Autores principales: Atsavapranee, Ella S., Billingsley, Margaret M., Mitchell, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099660/
https://www.ncbi.nlm.nih.gov/pubmed/33910123
http://dx.doi.org/10.1016/j.ebiom.2021.103354