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Forebrain-specific deficiency of the GTPase CRAG/Centaurin-γ3 leads to immature dentate gyri and hyperactivity in mice

Mouse models of various neuropsychiatric disorders, such as schizophrenia, often display an immature dentate gyrus, characterized by increased numbers of immature neurons and neuronal progenitors and a dearth of mature neurons. We previously demonstrated that the CRMP5-associated GTPase (CRAG), a sh...

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Detalles Bibliográficos
Autores principales: Nagashima, Shun, Ito, Naoki, Kobayashi, Reiki, Shiiba, Isshin, Shimura, Hiroki, Fukuda, Toshifumi, Hagihara, Hideo, Miyakawa, Tsuyoshi, Inatome, Ryoko, Yanagi, Shigeru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099661/
https://www.ncbi.nlm.nih.gov/pubmed/33811862
http://dx.doi.org/10.1016/j.jbc.2021.100620