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The Mediator complex kinase module is necessary for fructose regulation of liver glycogen levels through induction of glucose-6-phosphatase catalytic subunit (G6pc)

OBJECTIVE: Liver glycogen levels are dynamic and highly regulated by nutrient availability as the levels decrease during fasting and are restored during the feeding cycle. However, feeding in the presence of fructose in water suppresses glycogen accumulation in the liver by upregulating the expressi...

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Detalles Bibliográficos
Autores principales: Youn, Dou Yeon, Xiaoli, Alus M., Zong, Haihong, Okada, Junichi, Liu, Li, Pessin, Jacob, Pessin, Jeffrey E., Yang, Fajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099662/
https://www.ncbi.nlm.nih.gov/pubmed/33812059
http://dx.doi.org/10.1016/j.molmet.2021.101227