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The Mediator complex kinase module is necessary for fructose regulation of liver glycogen levels through induction of glucose-6-phosphatase catalytic subunit (G6pc)
OBJECTIVE: Liver glycogen levels are dynamic and highly regulated by nutrient availability as the levels decrease during fasting and are restored during the feeding cycle. However, feeding in the presence of fructose in water suppresses glycogen accumulation in the liver by upregulating the expressi...
Autores principales: | Youn, Dou Yeon, Xiaoli, Alus M., Zong, Haihong, Okada, Junichi, Liu, Li, Pessin, Jacob, Pessin, Jeffrey E., Yang, Fajun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099662/ https://www.ncbi.nlm.nih.gov/pubmed/33812059 http://dx.doi.org/10.1016/j.molmet.2021.101227 |
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