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Depletion of VPS35 attenuates metastasis of hepatocellular carcinoma by restraining the Wnt/PCP signaling pathway

Vesicle Protein Sorting 35 (VPS35) is a novel oncogene that promotes tumor growth through the PI3K/AKT signaling in hepatocellular carcinoma (HCC). However, the role of VPS35 in HCC metastasis and the underlying mechanisms remain largely unclear. In this study, we observed that overexpression of VPS...

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Detalles Bibliográficos
Autores principales: Liu, Yi, Deng, Haijun, Liang, Li, Zhang, Guiji, Xia, Jie, Ding, Keyue, Tang, Ni, Wang, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099696/
https://www.ncbi.nlm.nih.gov/pubmed/33997170
http://dx.doi.org/10.1016/j.gendis.2020.07.009