Evaluation by simulation of clinical trial designs for evaluation of treatment during a viral haemorrhagic fever outbreak

BACKGROUND: Viral haemorrhagic fevers are characterized by irregular outbreaks with high mortality rate. Difficulties arise when implementing therapeutic trials in this context. The outbreak duration is hard to predict and can be short compared to delays of trial launch and number of subject needed...

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Detalles Bibliográficos
Autores principales: Manchon, Pauline, Belhadi, Drifa, Mentré, France, Laouénan, Cédric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099711/
https://www.ncbi.nlm.nih.gov/pubmed/33952195
http://dx.doi.org/10.1186/s12874-021-01287-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099711/
https://www.ncbi.nlm.nih.gov/pubmed/33952195
http://dx.doi.org/10.1186/s12874-021-01287-w

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