Peroxiredoxin 2 oxidation reveals hydrogen peroxide generation within erythrocytes during high-dose vitamin C administration

Intravenous infusion of high dose (>10 g) vitamin C (IVC) is a common alternative cancer therapy. IVC results in millimolar levels of circulating ascorbate, which is proposed to generate cytotoxic quantities of H(2)O(2) in the presence of transition metal ions. In this study we report on the in v...

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Detalles Bibliográficos
Autores principales: Pearson, Andree G., Pullar, Juliet M., Cook, John, Spencer, Emma S., Vissers, Margreet CM., Carr, Anitra C., Hampton, Mark B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099772/
https://www.ncbi.nlm.nih.gov/pubmed/33905956
http://dx.doi.org/10.1016/j.redox.2021.101980

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099772/
https://www.ncbi.nlm.nih.gov/pubmed/33905956
http://dx.doi.org/10.1016/j.redox.2021.101980

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