A call for caution in analysing mammalian co-transfection experiments and implications of resource competition in data misinterpretation

Transient transfections are routinely used in basic and synthetic biology studies to unravel pathway regulation and to probe and characterise circuit designs. As each experiment has a component of intrinsic variability, reporter gene expression is usually normalized with co-delivered genes that act...

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Detalles Bibliográficos
Autores principales: Di Blasi, Roberto, Marbiah, Masue M., Siciliano, Velia, Polizzi, Karen, Ceroni, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099865/
https://www.ncbi.nlm.nih.gov/pubmed/33953169
http://dx.doi.org/10.1038/s41467-021-22795-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099865/
https://www.ncbi.nlm.nih.gov/pubmed/33953169
http://dx.doi.org/10.1038/s41467-021-22795-9

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