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The lncRNA Caren antagonizes heart failure by inactivating DNA damage response and activating mitochondrial biogenesis

In the past decade, many long noncoding RNAs (lncRNAs) have been identified and their in vitro functions defined, although in some cases their functions in vivo remain less clear. Moreover, unlike nuclear lncRNAs, the roles of cytoplasmic lncRNAs are less defined. Here, using a gene trapping approac...

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Detalles Bibliográficos
Autores principales: Sato, Michio, Kadomatsu, Tsuyoshi, Miyata, Keishi, Warren, Junco S., Tian, Zhe, Zhu, Shunshun, Horiguchi, Haruki, Makaju, Aman, Bakhtina, Anna, Morinaga, Jun, Sugizaki, Taichi, Hirashima, Kaname, Yoshinobu, Kumiko, Imasaka, Mai, Araki, Masatake, Komohara, Yoshihiro, Wakayama, Tomohiko, Nakagawa, Shinichi, Franklin, Sarah, Node, Koichi, Araki, Kimi, Oike, Yuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099897/
https://www.ncbi.nlm.nih.gov/pubmed/33953175
http://dx.doi.org/10.1038/s41467-021-22735-7