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Nicotine suppresses Parkinson’s disease like phenotypes induced by Synphilin-1 overexpression in Drosophila melanogaster by increasing tyrosine hydroxylase and dopamine levels

It has been observed that there is a lower Parkinson’s disease (PD) incidence in tobacco users. Nicotine is a cholinergic agonist and is the principal psychoactive compound in tobacco linked to cigarette addiction. Different studies have shown that nicotine has beneficial effects on sporadic and gen...

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Detalles Bibliográficos
Autores principales: Carvajal-Oliveros, Angel, Domínguez-Baleón, Carmen, Zárate, Rafaella V., Campusano, Jorge M., Narváez-Padilla, Verónica, Reynaud, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099903/
https://www.ncbi.nlm.nih.gov/pubmed/33953275
http://dx.doi.org/10.1038/s41598-021-88910-4