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Deep generative model embedding of single-cell RNA-Seq profiles on hyperspheres and hyperbolic spaces
Single-cell RNA-Seq (scRNA-seq) is invaluable for studying biological systems. Dimensionality reduction is a crucial step in interpreting the relation between cells in scRNA-seq data. However, current dimensionality reduction methods are often confounded by multiple simultaneous technical and biolog...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099904/ https://www.ncbi.nlm.nih.gov/pubmed/33953202 http://dx.doi.org/10.1038/s41467-021-22851-4 |