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Artemisinin susceptibility in the malaria parasite Plasmodium falciparum: propellers, adaptor proteins and the need for cellular healing

Studies of the susceptibility of Plasmodium falciparum to the artemisinin family of antimalarial drugs provide a complex picture of partial resistance (tolerance) associated with increased parasite survival in vitro and in vivo. We present an overview of the genetic loci that, in mutant form, can in...

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Detalles Bibliográficos
Autores principales: Sutherland, Colin J, Henrici, Ryan C, Artavanis-Tsakonas, Katerina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100002/
https://www.ncbi.nlm.nih.gov/pubmed/33095255
http://dx.doi.org/10.1093/femsre/fuaa056