Age-Related Changes in Thymic Central Tolerance

Thymic epithelial cells (TECs) and hematopoietic antigen presenting cells (HAPCs) in the thymus microenvironment provide essential signals to self-reactive thymocytes that induce either negative selection or generation of regulatory T cells (Treg), both of which are required to establish and maintai...

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Detalles Bibliográficos
Autores principales: Srinivasan, Jayashree, Lancaster, Jessica N., Singarapu, Nandini, Hale, Laura P., Ehrlich, Lauren I. R., Richie, Ellen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100025/
https://www.ncbi.nlm.nih.gov/pubmed/33968086
http://dx.doi.org/10.3389/fimmu.2021.676236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100025/
https://www.ncbi.nlm.nih.gov/pubmed/33968086
http://dx.doi.org/10.3389/fimmu.2021.676236

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