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Age-Related Changes in Thymic Central Tolerance

Thymic epithelial cells (TECs) and hematopoietic antigen presenting cells (HAPCs) in the thymus microenvironment provide essential signals to self-reactive thymocytes that induce either negative selection or generation of regulatory T cells (Treg), both of which are required to establish and maintai...

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Detalles Bibliográficos
Autores principales:	Srinivasan, Jayashree, Lancaster, Jessica N., Singarapu, Nandini, Hale, Laura P., Ehrlich, Lauren I. R., Richie, Ellen R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100025/ https://www.ncbi.nlm.nih.gov/pubmed/33968086 http://dx.doi.org/10.3389/fimmu.2021.676236

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