Collagen IV(α345) dysfunction in glomerular basement membrane diseases. I. Discovery of a COL4A3 variant in familial Goodpasture’s and Alport diseases

Diseases of the glomerular basement membrane (GBM), such as Goodpasture’s disease (GP) and Alport syndrome (AS), are a major cause of chronic kidney failure and an unmet medical need. Collagen IV(α345) is an important architectural element of the GBM that was discovered in previous research on GP an...

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Detalles Bibliográficos
Autores principales: Pokidysheva, Elena N., Seeger, Harald, Pedchenko, Vadim, Chetyrkin, Sergei, Bergmann, Carsten, Abrahamson, Dale, Cui, Zhao Wei, Delpire, Eric, Fervenza, Fernando C., Fidler, Aaron L., Fogo, Agnes B., Gaspert, Ariana, Grohmann, Maik, Gross, Oliver, Haddad, George, Harris, Raymond C., Kashtan, Clifford, Kitching, A. Richard, Lorenzen, Johan M., McAdoo, Stephen, Pusey, Charles D., Segelmark, Marten, Simmons, Alicia, Voziyan, Paul A., Wagner, Timo, Wüthrich, Rudolf P., Zhao, Ming-Hui, Boudko, Sergei P., Kistler, Andreas D., Hudson, Billy G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100070/
https://www.ncbi.nlm.nih.gov/pubmed/33774048
http://dx.doi.org/10.1016/j.jbc.2021.100590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100070/
https://www.ncbi.nlm.nih.gov/pubmed/33774048
http://dx.doi.org/10.1016/j.jbc.2021.100590

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