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Lipid binding by the N-terminal motif mediates plasma membrane localization of Bordetella effector protein BteA

The respiratory pathogens Bordetella pertussis and Bordetella bronchiseptica employ a type III secretion system (T3SS) to inject a 69-kDa BteA effector protein into host cells. This effector is known to contain two functional domains, including an N-terminal lipid raft targeting (LRT) domain and a c...

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Detalles Bibliográficos
Autores principales: Malcova, Ivana, Bumba, Ladislav, Uljanic, Filip, Kuzmenko, Darya, Nedomova, Jana, Kamanova, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100071/
https://www.ncbi.nlm.nih.gov/pubmed/33789161
http://dx.doi.org/10.1016/j.jbc.2021.100607