Beta-lactam-induced immediate hypersensitivity reactions: A genome-wide association study of a deeply phenotyped cohort

BACKGROUND: β-lactam antibiotics are associated with a variety of immune-mediated or hypersensitivity reactions, including immediate (type I) reactions mediated by antigen-specific IgE. OBJECTIVE: We sought to identify genetic predisposing factors for immediate reactions to β-lactam antibiotics. MET...

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Detalles Bibliográficos
Autores principales: Nicoletti, Paola, Carr, Daniel F., Barrett, Sarah, McEvoy, Laurence, Friedmann, Peter S., Shear, Neil H., Nelson, Matthew R., Chiriac, Anca M., Blanca-López, Natalia, Cornejo-García, José A., Gaeta, Francesco, Nakonechna, Alla, Torres, Maria J., Caruso, Cristiano, Valluzzi, Rocco L., Floratos, Aris, Shen, Yufeng, Pavlos, Rebecca K., Phillips, Elizabeth J., Demoly, Pascal, Romano, Antonino, Blanca, Miguel, Pirmohamed, Munir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mosby 2021
Materias:
Anaphylaxis, Drug Allergy, Urticaria, and Angioedema
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100096/
https://www.ncbi.nlm.nih.gov/pubmed/33058932
http://dx.doi.org/10.1016/j.jaci.2020.10.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100096/
https://www.ncbi.nlm.nih.gov/pubmed/33058932
http://dx.doi.org/10.1016/j.jaci.2020.10.004

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