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The ribosome modulates folding inside the ribosomal exit tunnel

Proteins commonly fold co-translationally at the ribosome, while the nascent chain emerges from the ribosomal exit tunnel. Protein domains that are sufficiently small can even fold while still located inside the tunnel. However, the effect of the tunnel on the folding dynamics of these domains is no...

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Detalles Bibliográficos
Autores principales: Wruck, Florian, Tian, Pengfei, Kudva, Renuka, Best, Robert B., von Heijne, Gunnar, Tans, Sander J., Katranidis, Alexandros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100117/
https://www.ncbi.nlm.nih.gov/pubmed/33953328
http://dx.doi.org/10.1038/s42003-021-02055-8