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The ribosome modulates folding inside the ribosomal exit tunnel
Proteins commonly fold co-translationally at the ribosome, while the nascent chain emerges from the ribosomal exit tunnel. Protein domains that are sufficiently small can even fold while still located inside the tunnel. However, the effect of the tunnel on the folding dynamics of these domains is no...
Autores principales: | Wruck, Florian, Tian, Pengfei, Kudva, Renuka, Best, Robert B., von Heijne, Gunnar, Tans, Sander J., Katranidis, Alexandros |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100117/ https://www.ncbi.nlm.nih.gov/pubmed/33953328 http://dx.doi.org/10.1038/s42003-021-02055-8 |
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