SOX2 promotes chemoresistance, cancer stem cells properties, and epithelial–mesenchymal transition by β-catenin and Beclin1/autophagy signaling in colorectal cancer

Sex-determining region Y-box2 (SOX2), a master regulator of embryonic and induced pluripotent stem cells, drives cancer stem cells (CSCs) properties, fuels tumor initiation, and contributes to tumor aggressiveness. Our previous study has demonstrated the oncogenic role of SOX2 in colorectal cancer (...

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Detalles Bibliográficos
Autores principales: Zhu, Yin, Huang, Shimiao, Chen, Shengyuan, Chen, Jiaxuan, Wang, Zhiqing, Wang, Yadong, Zheng, Haoxuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100126/
https://www.ncbi.nlm.nih.gov/pubmed/33953166
http://dx.doi.org/10.1038/s41419-021-03733-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100126/
https://www.ncbi.nlm.nih.gov/pubmed/33953166
http://dx.doi.org/10.1038/s41419-021-03733-5

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