Highly chemoselective synthesis of hindered amides via cobalt-catalyzed intermolecular oxidative hydroamidation

α-Tertiary amides are of great importance for medicinal chemistry. However, they are often challenging to access through conventional methods due to reactivity and chemoselectivity issues. Here, we report a single-step approach towards such amides via cobalt-catalyzed intermolecular oxidative hydroa...

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Detalles Bibliográficos
Autores principales: Yin, Yun-Nian, Ding, Rui-Qi, Ouyang, Dong-Chen, Zhang, Qing, Zhu, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100129/
https://www.ncbi.nlm.nih.gov/pubmed/33953181
http://dx.doi.org/10.1038/s41467-021-22373-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100129/
https://www.ncbi.nlm.nih.gov/pubmed/33953181
http://dx.doi.org/10.1038/s41467-021-22373-z

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