Efficient genome editing of an extreme thermophile, Thermus thermophilus, using a thermostable Cas9 variant

Thermophilic organisms are extensively studied in industrial biotechnology, for exploration of the limits of life, and in other contexts. Their optimal growth at high temperatures presents a challenge for the development of genetic tools for their genome editing, since genetic markers and selection...

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Detalles Bibliográficos
Autores principales: Adalsteinsson, Bjorn Thor, Kristjansdottir, Thordis, Merre, William, Helleux, Alexandra, Dusaucy, Julia, Tourigny, Mathilde, Fridjonsson, Olafur, Hreggvidsson, Gudmundur Oli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100143/
https://www.ncbi.nlm.nih.gov/pubmed/33953310
http://dx.doi.org/10.1038/s41598-021-89029-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100143/
https://www.ncbi.nlm.nih.gov/pubmed/33953310
http://dx.doi.org/10.1038/s41598-021-89029-2

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