Concurrent X chromosome inactivation and upregulation during non-human primate preimplantation development revealed by single-cell RNA-sequencing

In mammals, dosage compensation of X-linked gene expression between males and females is achieved by inactivation of a single X chromosome in females, while upregulation of the single active X in males and females leads to X:autosome dosage balance. Studies in human embryos revealed that random X ch...

Descripción completa

Detalles Bibliográficos
Autores principales: Cidral, Ana Luíza, de Mello, Joana C. Moreira, Gribnau, Joost, Pereira, Lygia V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100148/
https://www.ncbi.nlm.nih.gov/pubmed/33953270
http://dx.doi.org/10.1038/s41598-021-89175-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100148/
https://www.ncbi.nlm.nih.gov/pubmed/33953270
http://dx.doi.org/10.1038/s41598-021-89175-7

Ejemplares similares