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Stochastic Episodes of Latent Cytomegalovirus Transcription Drive CD8 T-Cell “Memory Inflation” and Avoid Immune Evasion

Acute infection with murine cytomegalovirus (mCMV) is controlled by CD8(+) T cells and develops into a state of latent infection, referred to as latency, which is defined by lifelong maintenance of viral genomes but absence of infectious virus in latently infected cell types. Latency is associated w...

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Detalles Bibliográficos
Autores principales: Griessl, Marion, Renzaho, Angelique, Freitag, Kirsten, Seckert, Christof K., Reddehase, Matthias J., Lemmermann, Niels A. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100209/
https://www.ncbi.nlm.nih.gov/pubmed/33968074
http://dx.doi.org/10.3389/fimmu.2021.668885