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Stochastic Episodes of Latent Cytomegalovirus Transcription Drive CD8 T-Cell “Memory Inflation” and Avoid Immune Evasion
Acute infection with murine cytomegalovirus (mCMV) is controlled by CD8(+) T cells and develops into a state of latent infection, referred to as latency, which is defined by lifelong maintenance of viral genomes but absence of infectious virus in latently infected cell types. Latency is associated w...
Autores principales: | Griessl, Marion, Renzaho, Angelique, Freitag, Kirsten, Seckert, Christof K., Reddehase, Matthias J., Lemmermann, Niels A. W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100209/ https://www.ncbi.nlm.nih.gov/pubmed/33968074 http://dx.doi.org/10.3389/fimmu.2021.668885 |
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