Mitochondrial CHCHD2: Disease-Associated Mutations, Physiological Functions, and Current Animal Models

Rare mutations in the mitochondrial protein coiled-coil-helix-coiled-coil-helix domain containing 2 (CHCHD2) are associated with Parkinson’s disease (PD) and other Lewy body disorders. CHCHD2 is a bi-organellar mediator of oxidative phosphorylation, playing crucial roles in regulating electron flow...

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Detalles Bibliográficos
Autores principales: Kee, Teresa R., Espinoza Gonzalez, Pamela, Wehinger, Jessica L., Bukhari, Mohammed Zaheen, Ermekbaeva, Aizara, Sista, Apoorva, Kotsiviras, Peter, Liu, Tian, Kang, David E., Woo, Jung-A. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100248/
https://www.ncbi.nlm.nih.gov/pubmed/33967741
http://dx.doi.org/10.3389/fnagi.2021.660843

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100248/
https://www.ncbi.nlm.nih.gov/pubmed/33967741
http://dx.doi.org/10.3389/fnagi.2021.660843

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