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Bile Acids Elevated in Chronic Periaortitis Could Activate Farnesoid-X-Receptor to Suppress IL-6 Production by Macrophages

Chronic periaortitis (CP) is a rare autoimmune disease without effective treatment. By analyzing the serum bile acid spectrum in 28 CP patients with the ultra-performance liquid chromatography-tandem mass spectrometry, we found that the bile acids were significantly altered in CP patients, with sign...

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Detalles Bibliográficos
Autores principales: Cao, Shan, Meng, Xinyu, Li, Yixuan, Sun, Li, Jiang, Lindi, Xuan, Hanqing, Chen, Xiaoxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100322/
https://www.ncbi.nlm.nih.gov/pubmed/33968024
http://dx.doi.org/10.3389/fimmu.2021.632864