PD-L1 Blockade During Allergen Sensitization Inhibits the Synthesis of Specific Antibodies and Decreases Mast Cell Activation in a Murine Model of Active Cutaneous Anaphylaxis

Programmed cell death ligand 1(PDL-1) is known for its inhibitory effect on the cellular immune response. Even though it is expressed on the surface of mast cells, its role in allergic diseases is unknown. We analyzed the effects of PD-L1 blockade in a murine model of active cutaneous anaphylaxis (A...

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Detalles Bibliográficos
Autores principales: Bonamichi-Santos, Rafael, Aun, Marcelo Vivolo, Kalil, Jorge, Castells, Mariana Concepcion, Giavina-Bianchi, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100332/
https://www.ncbi.nlm.nih.gov/pubmed/33968057
http://dx.doi.org/10.3389/fimmu.2021.655958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100332/
https://www.ncbi.nlm.nih.gov/pubmed/33968057
http://dx.doi.org/10.3389/fimmu.2021.655958

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