Endothelial eNAMPT amplifies pre-clinical acute lung injury: efficacy of an eNAMPT-neutralising monoclonal antibody

RATIONALE: The severe acute respiratory syndrome coronavirus 2/coronavirus disease 2019 pandemic has highlighted the serious unmet need for effective therapies that reduce acute respiratory distress syndrome (ARDS) mortality. We explored whether extracellular nicotinamide phosphoribosyltransferase (...

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Detalles Bibliográficos
Autores principales: Quijada, Hector, Bermudez, Tadeo, Kempf, Carrie L., Valera, Daniel G., Garcia, Alexander N., Camp, Sara M., Song, Jin H., Franco, Evelyn, Burt, Jessica K., Sun, Belinda, Mascarenhas, Joseph B., Burns, Kimberlie, Gaber, Amir, Oita, Radu C., Reyes Hernon, Vivian, Barber, Christy, Moreno-Vinasco, Liliana, Sun, Xiaoguang, Cress, Anne E., Martin, Diego, Liu, Zhonglin, Desai, Ankit A., Natarajan, Viswanathan, Jacobson, Jeffrey R., Dudek, Steven M., Bime, Christian, Sammani, Saad, Garcia, Joe G.N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100338/
https://www.ncbi.nlm.nih.gov/pubmed/33243842
http://dx.doi.org/10.1183/13993003.02536-2020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100338/
https://www.ncbi.nlm.nih.gov/pubmed/33243842
http://dx.doi.org/10.1183/13993003.02536-2020

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