Synergistic effect of Chloroquine and Panobinostat in ovarian cancer through induction of DNA damage and inhibition of DNA repair

Ovarian cancer (OC) is the deadliest gynecologic malignancy, which is mainly due to late-stage diagnosis and chemotherapy resistance. Therefore, new and more effective treatments are urgently needed. The in vitro effects of Panobinostat (LBH), a histone deacetylase inhibitor that exerts pleiotropic...

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Detalles Bibliográficos
Autores principales: Ovejero-Sánchez, María, González-Sarmiento, Rogelio, Herrero, Ana Belén
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100353/
https://www.ncbi.nlm.nih.gov/pubmed/33930758
http://dx.doi.org/10.1016/j.neo.2021.04.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100353/
https://www.ncbi.nlm.nih.gov/pubmed/33930758
http://dx.doi.org/10.1016/j.neo.2021.04.003

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