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Synergistic effect of Chloroquine and Panobinostat in ovarian cancer through induction of DNA damage and inhibition of DNA repair
Ovarian cancer (OC) is the deadliest gynecologic malignancy, which is mainly due to late-stage diagnosis and chemotherapy resistance. Therefore, new and more effective treatments are urgently needed. The in vitro effects of Panobinostat (LBH), a histone deacetylase inhibitor that exerts pleiotropic...
Autores principales: | Ovejero-Sánchez, María, González-Sarmiento, Rogelio, Herrero, Ana Belén |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100353/ https://www.ncbi.nlm.nih.gov/pubmed/33930758 http://dx.doi.org/10.1016/j.neo.2021.04.003 |
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