Valproic Acid Protects Chondrocytes from LPS-Stimulated Damage via Regulating miR-302d-3p/ITGB4 Axis and Mediating the PI3K-AKT Signaling Pathway

Background: Osteoarthritis (OA) is one of the most common degenerative joint diseases characterized by increased apoptosis and autophagy deficiency. The investigation was performed to examine the effect of valproic acid (VPA) and molecular mechanism related to miR-302d-3p/ITGB4 axis in OA. Methods:...

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Detalles Bibliográficos
Autores principales: Sun, Long, Zheng, Wei, Liu, Qian-Dong, Ge, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100442/
https://www.ncbi.nlm.nih.gov/pubmed/33968981
http://dx.doi.org/10.3389/fmolb.2021.633315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100442/
https://www.ncbi.nlm.nih.gov/pubmed/33968981
http://dx.doi.org/10.3389/fmolb.2021.633315

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