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Competence Mining of Vancomycin (VAN) in the Management of Infections Due to Bacterial Strains With High VAN Minimum Inhibitory Concentrations (MICs): A Novel Dosing Strategy Based on Pharmacokinetic/Pharmacodynamic Modeling

The increasing emergence of bacterial strains with high VAN MICs (BS(H)(–)(V)(AN–)(M)), such as Enterococcus faecalis, Enterococcus faecium, Staphylococcus aureus, Staphylococcus epidermidis, and Streptococcus bovis, results in growing concern that VAN is not effective against these isolates. Due to...

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Detalles Bibliográficos
Autores principales: Song, Xiangqing, Zeng, Meizi, Wu, Yi, Pan, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100448/
https://www.ncbi.nlm.nih.gov/pubmed/33967986
http://dx.doi.org/10.3389/fmicb.2021.649757