The Effect of Cholesterol on Membrane-Bound Islet Amyloid Polypeptide

Islet amyloid polypeptide (IAPP) is a proposed cause of the decreased beta-cell mass in patients with type-II diabetes. The molecular composition of the cell-membrane is important for regulating IAPP cytotoxicity and aggregation. Cholesterol is present at high concentrations in the pancreatic beta-c...

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Detalles Bibliográficos
Autores principales: Christensen, Mikkel, Berglund, Nils A., Schiøtt, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100463/
https://www.ncbi.nlm.nih.gov/pubmed/33968989
http://dx.doi.org/10.3389/fmolb.2021.657946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100463/
https://www.ncbi.nlm.nih.gov/pubmed/33968989
http://dx.doi.org/10.3389/fmolb.2021.657946

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