Cryptotanshinone Inhibits ERα-Dependent and -Independent BCRP Oligomer Formation to Reverse Multidrug Resistance in Breast Cancer

Both long-term anti-estrogen therapy and estrogen receptor-negative breast cancer contribute to drug resistance, causing poor prognosis in breast cancer patients. Breast cancer resistance protein (BCRP) plays an important role in multidrug resistance. Here, we show that cryptotanshinone (CPT), an an...

Descripción completa

Detalles Bibliográficos
Autores principales: Ni, Wenting, Fan, Hui, Zheng, Xiuqin, Xu, Fangming, Wu, Yuanyuan, Li, Xiaoman, Wang, Aiyun, Huang, Shile, Chen, Wenxing, Wang, Shijun, Lu, Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100513/
https://www.ncbi.nlm.nih.gov/pubmed/33968724
http://dx.doi.org/10.3389/fonc.2021.624811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100513/
https://www.ncbi.nlm.nih.gov/pubmed/33968724
http://dx.doi.org/10.3389/fonc.2021.624811

Ejemplares similares